The label will show “Guaranteed GMP Product.” This isn’t just for taurine but all supplements.įortunately, there are many very good, reliable supplement producers as well as those linked to what is known as ‘professional grade’ supplements that are viable options. I always want to know about the producer’s compliance with FDA Good Manufacturing Practices (GMPs). There are a lot of supplements that may not be derived from pure raw-material sources and also can have inferior quality control or no quality control that can lead to various forms of contamination.
Because I have a history of MCS, I have to be very careful to choose a reputable source which can mean it can cost more. Often, those reactions such as afib can be linked to the quality and ‘pureness’ of the product, itself, the ‘fillers’ added or even the quality control of the manufacturing facility. Cataloging what we know of taurine function, however, produces a list of "maybes." Now is the time for exhaustive, careful taurine research that will produce more definite answers.Yes, Susan, thanks - that's true with just about any supplement. Taurine has recently been added to infant formulas (about 50 mg/L). We have begun to appreciate the role of the kidney in conserving taurine and how this is perturbed in the neonatal period. Prolonged TPN feeding of infants demonstrates the importance of taurine in retinal development. Evidence is strong that taurine is vital in maintaining retinal function, which may explain why taurine is so abundant in human breast milk. Taurine may play this role in the brain under high osmotic states such as hypernatremia, dehydration and uremia.
The abundance of taurine suggests it may be an osmoregulator of cell volume, and there is convincing evidence that it serves this function in fish.
The finding that taurine availability protects against cholestasis induced by monohydroxy bile acids remains confined to guinea pigs. Biliary cholesterol saturation also stays the same. Unchanged are the rate of bile acid synthesis or the secretion rates of biliary cholesterol, bile acid and phospholipids. Total pool size of bile acid and chenodeoxycholic acid declines. While taurine conjugation is the preferred route of bile acid conjugation in the young, changes in adults given 250 mg of taurine daily for two to three weeks are insignificant. Given this abundance of taurine, why is our understanding of its function so elusive? Although it is clear taurine is important in conjugating bile acids to form water-soluble bile salts, only a fraction of available taurine is used for this function, predominantly in young animals and children. In cardiac tissue alone, taurine levels of 20 mM or higher may be found. Both the biomedical investigator and clinician must be struck by the enormous amount of taurine floating freely in the intracellular water of the cells. More than simply cataloging the numerous experimental models in which taurine plays a modulating role, this discussion aims at stimulating further investigation of the potential clinical value of this abundant sulfur amino acid.
0 kommentar(er)
